Observational Study of the Epidemiological, Clinical, and Diagnostic Profile, Treatment Patterns, and Outcomes of Lung Cancer.

Status: Recruiting
Location: See all (21) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

SAFRO 2202 ALG-Lung Cancer Registry is a prospective, multicenter, non-interventional observational study conducted across 21 public and university hospitals in Algeria. The objective is to characterize the epidemiological, clinical, pathological, molecular, and therapeutic features of patients diagnosed with lung cancer, including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), and carcinoid tumors. Eligible participants are adults aged 18 years or older, diagnosed at the time of inclusion or within the previous 12 months, and fully managed in oncology or pulmonology departments. Data are collected during routine clinical care and recorded in a secure electronic case report form (eCRF). No protocol-mandated interventions or study-specific visits are required. The study plans to enroll approximately 1,500 patients per year over a 30-month period. Primary outcomes include demographic and clinical profiles, tumor histology, molecular markers, staging at diagnosis, and treatment strategies (surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy). Secondary outcomes include treatment-related toxicities, objective response rate (ORR), progression-free survival (PFS), time to treatment discontinuation (TTD), and overall survival (OS). The findings from this registry will provide real-world evidence to support national health planning, improve lung cancer management, and guide future clinical and public health initiatives in Algeria.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years

• Histologically confirmed diagnosis of lung cancer (NSCLC, SCLC, or carcinoid tumor)

• Diagnosed at the time of inclusion or within the 12 previous months

• Fully managed (diagnosis, treatment, and follow-up) in an oncology or pulmonology department of one of the 21 participating public/university hospitals

• Signed informed consent obtained

Locations
Other Locations
Algeria
Centre Pierre et Marie Curie
RECRUITING
Algiers
Chu Beni Messous - Isaad Hassani
RECRUITING
Algiers
CHU Mohamed Lamine Debaghine - Bab-el-Oued
RECRUITING
Algiers
Chu-Beni Messous - Isaad Hassani
RECRUITING
Algiers
EPH Rouiba
RECRUITING
Algiers
CLCC Annaba
RECRUITING
Annaba
CLCC Batna
RECRUITING
Batna City
CHU- Hôpital Khelil Amrane
RECRUITING
Béjaïa
CAC-CHU Frantz Fanon
RECRUITING
Blida
CHU Dr Abdesselam Benbadis
RECRUITING
Constantine
EH Didouche Mourad
RECRUITING
Constantine
CAC El OUED
RECRUITING
El Oued
CAC-Laghouat
RECRUITING
Laghouat
CAC Oran EL HASSI- EMIR ABDELKADER
RECRUITING
Oran
CHU Dr. Benaouda Benzerdjeb
RECRUITING
Oran
EHS 1er novembre
RECRUITING
Oran
CAC- Ouargla
RECRUITING
Ouargla
CAC-Sétif
RECRUITING
Sétif
CAC- Sidi Bel Abbès
RECRUITING
Sidi Bel Abbes
EPH- Sidi Ghiles
RECRUITING
Tipasa
CLCC Draâ Ben Khedda
RECRUITING
Tizi Ouzou
Contact Information
Primary
Louisa ISSIAKHEM LOUNICI, CEO
l.issiakhem@cmsolutionsdz.com
+213 770 48 43 36
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2027-12
Participants
Target number of participants: 3750
Treatments
Lung Cancer Patients Cohort
Adult patients (≥18 years) diagnosed with lung cancer (NSCLC, SCLC, or carcinoid tumors) at the time of inclusion or within the previous 12 months, fully managed in oncology or pulmonology departments at one of the 21 participating public or university hospitals across Algeria. Data are collected prospectively during routine clinical care.
Sponsors
Leads: Société Algérienne de Formation et de Recherche en Oncologie
Collaborators: AstraZeneca

This content was sourced from clinicaltrials.gov

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